Is high risk of cardiovascular disease if diagnosed as diabetes at childhood?

Children diagnosed with type 1 diabetes have a 30 times risk of cardiovascular disease!

Although it is a bit shocking story, children diagnosed with type 1 diabetes by 10 years old are likely to have a higher risk of developing cardiovascular disease and premature death.

Compared with healthy subjects, the risk of developing coronary artery disease and acute myocardial infarction is about 30 times in patients diagnosed with type 1 diabetes by 10 years of age, about 6 times in patients diagnosed between 26 and 30 years of age.

Based on this result, researchers thought that “If you are diagnosed with type 1 diabetes when you are a child, you should take medicine such as statins and antihypertensive drugs as soon as possible”.

But do they really have to take medicine? I think that sometimes it is necessary to take medicine if necessary, but what else can they do?

 

 

And I think that this is not only a problem of type 1 diabetic patients but also type 2 diabetic patients.

Type 1 often develops as a child, so it will become easier for problems as Luo disease period becomes longer.

Now, let’s think about how to reduce the risk of cardiovascular disease after developing diabetes in children and young people.

 

Nyago
What! The risk of developing coronary artery disease and acute myocardial infarction is 30 times!?

Yosshie
I think that parents with children with type 1 diabetes are very sad…

 

Why diabetes patients are prone to cardiovascular disease?

All diabetic patients are at high risk of cardiovascular disease because they tend to develop arteriosclerosis.

We know that arteriosclerosis has already proceeded from the stage called “pre-stage of diabetes”.

Even if arteriosclerosis occurs, there is almost no subjective symptom until it progresses considerably.

The mass called “plaque” that can be formed in the blood vessel suddenly ruptures, creates a thrombus, and occasionally blocks the interior of the blood vessel.

 

 

This is why people who have been energetic suddenly suffer from cerebral infarction or myocardial infarction attacks!

Three major complications of diabetes (neuropathy, retinopathy, nephropathy) have a higher incidence as HbA1c increases, but cardiovascular disease occurs considerably even if HbA1c is less than 7%.

Why are diabetic patients easy to progress arteriosclerosis?

 

What causes arteriosclerosis to proceed?

One of the causes of arteriosclerosis is high blood sugar level (especially postprandial blood sugar level).

When eating a lot of carbohydrates and after eating hyperglycemia, the vascular endothelium is scratched, and cholesterol enters from there.

This happens when the blood sugar level rises, so remember that arteriosclerosis will proceed if LDL cholesterol is normal but there is postprandial hyperglycemia!

If you are visceral fat type obesity, arteriosclerosis is easy to progress due to hyperlipemia, fatty liver, diabetes.

Overdose of fructose is the cause of increased neutral fat and arteriosclerosis, Fructose is easy to get to neutral fat, it is easy to make AGEs (final glycation products).

 



 

AGEs cause arteriosclerosis and cause aging, wrinkles, cataracts, etc.

Some people argue that “fruits are rich in vitamins, minerals and dietary fiber, so they are good for the body”, but vitamins, minerals and dietary fiber can be ingested from other vegetables.

“Artificial trans fatty acids” that are regulated in the United States etc. also cause arteriosclerosis to progress.

School lunch bread and fast food, a lot of prepared dishes, eating out, snacks, etc. In Japan, there is no obligation to display trans fatty acids so it is in a relieved state…

And this may be the most important, but “hyperinsulinemia” will progress arteriosclerosis.

 

What causes hyperinsulinemia?

It is very shocking that hyperinsulinemia progresses arteriosclerosis and causes various diabetic complications.

Because many Japanese diabetic patients are told that at hospitals “If you use insulin injection (or insulin secretion medicine) you can normally eat whatever you want”.

But at least thirty years ago, Japanese doctors knew that hyperinsulinemia caused arteriosclerosis … they do not explain to patients!

When there is insulin resistance, that is, insulin is ineffective, pancreatic β cells try to cover a large amount of insulin by that amount.

 

 

This is what happens to obese Mild Type 2 diabetic patients and gestational diabetes patients.

Obesity reduces the effectiveness of insulin, and during pregnancy a hormone is given which will make insulin less effective from the placenta.

Diabetic patients with type 2 diabetes obesity sholud get normal weight.  Some people dramatically improve blood glucose as it loses insulin resistance.

The problem is type 1 diabetic patients. There are cases where obese subjects develop type 1 diabetes, but in principle type 1 people do not have insulin resistance.

 

What problems are likely to occur in patients with type 1 diabetes?

Type 1 diabetic patients inject insulin that can not be secreted by beta cells of their own pancreas.

“If so, patients with type 1 diabetes will not change anything from healthy people,” but they are not the same.

If heavy hypoglycemia occurs, myocardial infarction and stroke are likely to occur, in both type 1 diabetics or type 2 diabetes.

Healthy people will never cause heavy hypoglycemia, because their insulin secretion is adjusted with exquisite amounts and timings.

 

 

But diabetics who are taking bolus insulin injections often cause hypoglycemia. It is incorrect that “It will not change anything from healthy people if you hit insulin”.

In Japan, I feel that people with type 1 diabetes who are on low carbohydrate diets are less than type 2.

Most type 2 diabetic patients don’t need insulin injection with a low carbohydrate diet, while insulin injections are absolutely necessary for type 1 diabetic patients to survive.

It is natural for people of type 1 diabetes to think that “We need insulin injections, so we want to eat whatever we like”.

 

Low carbohydrate diet reduce the risk of cardiovascular disease

For both diabetic and non-diabetic people, the more you ingest carbohydrates, the better the risk of cardiovascular disease will be.

Patients with type 1 diabetes or type 2 diabetes who is injecting bolus insulin tend to suffer hypoglycemia, which raises the risk of myocardial infarction and stroke.

Patients with mild type 2 diabetes who do not have insulin injection, especially those who are obese type and who have strong insulin resistance or eat a large amount of sugar, will develop arteriosclerosis due to hyperinsulinemia.

Dr. Richard K. Bernstein, who developed type 1 diabetes at the age of 12, is on a low carbohydrate diet. His insulin injection volume is basal 6 units plus bolus 10 units (per day), so it is difficult for hypoglycemia to occur, and He is  fine even though he is 84 years old.

 

 

For the health of children with diabetes, it is important not to cause going up and down like a roller coaster of their blood sugar as much as possible.

Children should not lose the pleasure of eating what they want to eat, but it is wrong to say ” if you use insulin injection(or medicine) you can eat whatever you want”.

Parents should think about what to do in order to protect their children’s health while consider of pleasure to eat.

 

Nyago
It is not an unavoidable fate because it is diabetes, there are means to prevent it!

Yosshie
That’s right! You do not have to despair.